I upgraded from 8.04LTS to 8.10 yesterday, and it has been nothing but trouble ever since. I had to manually get X working (since there are some problems with the ATI driver obviously), f-spot stopped working (some strange X-windows error), CIFS mounts now complain about being unable to load NLS codepage cp437 (and therefore filling up the syslog with several entries every second), and I will probably find more when I progress on using the system.
This SUCKS big time. I know 8.10 is not an LTS version, but it should be a stable version. I beg to differ.
Update: Azureus (now Vuze) has an auto-update bug (downloads 4.0.0.4, installs and restarts, but remains 3.1.1.0, so wants to update again)